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Kazuo Nakamura Selected Research

Diabetic Angiopathies (Diabetic Angiopathy)

11/2008Pigment epithelium-derived factor (PEDF): its potential therapeutic implication in diabetic vascular complications.
7/2008Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular complications.
1/2008Receptor for advanced glycation end products (RAGE): a novel therapeutic target for diabetic vascular complication.
1/2008Telmisartan inhibits advanced glycation end products (AGEs)-elicited endothelial cell injury by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gammaactivation.
1/2008Role of asymmetric dimethylarginine (ADMA) in diabetic vascular complications.
7/2007Elevation of soluble form of receptor for advanced glycation end products (sRAGE) in diabetic subjects with coronary artery disease.
7/2007Advanced glycation end products (AGEs) and cardiovascular disease (CVD) in diabetes.
9/2006Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects.
3/2006Advanced glycation end products (AGEs) and their receptor (RAGE) system in diabetic retinopathy.
1/2006Atorvastatin and diabetic vascular complications.
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Kazuo Nakamura Research Topics

Disease

17Atherosclerosis
09/2009 - 05/2004
15Diabetic Retinopathy (Retinopathy, Diabetic)
01/2008 - 08/2004
12Diabetic Angiopathies (Diabetic Angiopathy)
11/2008 - 02/2005
7Cardiovascular Diseases (Cardiovascular Disease)
05/2010 - 01/2006
5Inflammation (Inflammations)
01/2017 - 01/2006
5Neoplasms (Cancer)
07/2012 - 12/2004
5Hyperglycemia
01/2008 - 02/2006
5Hypertension (High Blood Pressure)
01/2008 - 12/2003
4Metabolic Syndrome (Dysmetabolic Syndrome X)
08/2010 - 06/2006
4Type 2 Diabetes Mellitus (MODY)
01/2009 - 03/2007
4Ischemia
01/2009 - 03/2006
4Reperfusion Injury
11/2007 - 03/2006
3Insulin Resistance
08/2010 - 08/2007
3Thrombosis (Thrombus)
04/2010 - 03/2008
3Infarction (Infarctions)
01/2009 - 03/2006
3Coronary Artery Disease (Coronary Atherosclerosis)
05/2008 - 01/2006
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2008 - 02/2006
3Uveitis
09/2007 - 02/2007
3Stroke (Strokes)
02/2005 - 01/2002
2Fibrosis (Cirrhosis)
01/2017 - 01/2008
2Obesity
01/2015 - 10/2013
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2014 - 07/2012
2Essential Hypertension
08/2010 - 11/2005
2Acute Coronary Syndrome
03/2008 - 01/2006
2Necrosis
02/2008 - 02/2007
2Vascular System Injuries
01/2008 - 06/2007
2Eye Diseases (Eye Disease)
01/2007 - 11/2005
2Hepatocellular Carcinoma (Hepatoma)
10/2006 - 05/2006
1Fatty Liver
01/2017
1GM2 Gangliosidoses (GM2 Gangliosidosis)
06/2014
1Carcinoma (Carcinomatosis)
10/2013
1Chronic Hepatitis C
02/2013
1Colonic Neoplasms (Colon Cancer)
01/2012
1Leukemia
12/2010
1Psoriasis (Pustulosis Palmaris et Plantaris)
03/2010
1Critical Illness (Critically Ill)
12/2009
1Sepsis (Septicemia)
12/2009
1Atrial Fibrillation
08/2009

Drug/Important Bio-Agent (IBA)

27pigment epithelium-derived factorIBA
01/2017 - 08/2004
26Advanced Glycation End ProductsIBA
09/2009 - 02/2005
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2009 - 05/2004
7Receptor for Advanced Glycation End ProductsIBA
09/2009 - 11/2005
7Angiotensin IIIBA
01/2008 - 06/2005
6Biomarkers (Surrogate Marker)IBA
09/2009 - 03/2007
5Proteins (Proteins, Gene)FDA Link
12/2009 - 01/2005
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2008 - 12/2004
5Telmisartan (Micardis)FDA Link
01/2008 - 11/2005
4P-SelectinIBA
04/2010 - 03/2006
4NADPH Oxidases (NAD(P)H oxidase)IBA
03/2008 - 06/2005
4Retinaldehyde (Retinal)IBA
07/2007 - 01/2005
3GhrelinIBA
01/2015 - 02/2005
3Angiotensin II Type 1 Receptor BlockersIBA
01/2008 - 01/2008
3NitrogenIBA
01/2008 - 12/2004
3Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2008 - 03/2002
2Cisplatin (Platino)FDA LinkGeneric
02/2014 - 07/2012
2Glycoproteins (Glycoprotein)IBA
02/2013 - 04/2010
2AntigensIBA
01/2012 - 12/2010
2C-Reactive ProteinIBA
09/2009 - 05/2006
2TaurineFDA Link
01/2009 - 05/2007
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2008 - 07/2006
2Superoxides (Superoxide)IBA
03/2008 - 06/2007
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
02/2008 - 06/2007
2oxidized low density lipoproteinIBA
01/2008 - 05/2007
2Urea (Carbamide)FDA LinkGeneric
01/2008 - 11/2007
2Fatty Acid-Binding ProteinsIBA
01/2008 - 11/2007
2CalciumIBA
01/2008 - 01/2006
21,4-dihydropyridine (dihydropyridine)IBA
01/2008 - 01/2006
2PPAR gammaIBA
01/2008 - 01/2008
2Nifedipine (Adalat)FDA LinkGeneric
01/2008 - 01/2006
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2008 - 06/2007
2AntioxidantsIBA
09/2007 - 05/2007
2DNA (Deoxyribonucleic Acid)IBA
07/2007 - 12/2004
2CytokinesIBA
01/2006 - 02/2005
2aniracetamIBA
03/2002 - 01/2002
1G(M2) Ganglioside (Ganglioside GM2)IBA
06/2014
1LipofuscinIBA
06/2014
1octanoic acid (caprylic acid)IBA
10/2013
1EnzymesIBA
10/2013
1Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
10/2013
1CryoglobulinsIBA
02/2013
1Antineoplastic Agents (Antineoplastics)IBA
07/2012
1MucinsIBA
01/2012
1EpitopesIBA
12/2010
1gamma-sitosterol (beta-sitosterol)IBA
05/2010
1CholesterolIBA
05/2010
1Angiogenic ProteinsIBA
03/2010
1Peptides (Polypeptides)IBA
03/2010
1HMGB1 Protein (HMG1)IBA
12/2009
1PPAR-gamma AgonistsIBA
09/2009
1Triglycerides (Triacylglycerol)IBA
09/2009
1Insulin (Novolin)FDA Link
09/2009
1AcidsIBA
09/2009
1Fibrinogen (Factor I)FDA Link
09/2009
1HDL CholesterolIBA
09/2009
1CreatinineIBA
09/2009
1Glucose (Dextrose)FDA LinkGeneric
08/2009
1CD40 Ligand (CD40L)IBA
04/2009
1Lactic Acid (Lactate)FDA LinkGeneric
01/2009
1Creatine Kinase (Creatine Phosphokinase)IBA
01/2009

Therapy/Procedure

6Therapeutics
07/2012 - 01/2006